
In this episode, Dr. Ben Bikman exposes the dietary culprits that drive metabolic dysfunction and highlights actionable, evidence-based tactics for improving metabolic health. Ben also addresses pressing questions about popular weight loss medications like Ozempic and other GLP-1 agonists: Are they groundbreaking solutions, or shortcuts with hidden metabolic consequences? Timestamps: (0:00) Introduction (4:51) Can you be insulin resistant with normal glucose levels? (8:30) Can glucose monitors detect hidden insulin resistance? (10:01) What your skin reveals about insulin resistance (11:25) Why is insulin resistance behind so many chronic diseases? (15:46) Does obesity cause insulin resistance—or vice versa? (22:38) Insulin's surprising roles beyond blood sugar control (23:36) What's driving weight gain—insulin or calories? (30:30) Do saturated fats cause insulin resistance? (37:02) Why refined carbs amplify risks from saturated fat (40:04) Fructose vs. refined sugar—which spikes insulin more? (41:01) High-carb vs. keto—which diet controls hunger better? (45:27) Why low-carb diets might provide a metabolic advantage (47:36) Does exercise give you metabolic 'wiggle room'? (52:00) Why strength training beats cardio for insulin sensitivity (54:03) Should you lower insulin before cutting calories? (57:12) Does meal frequency drive insulin resistance? (1:00:32) Is nighttime snacking giving you insomnia? (1:02:24) Can a sugary breakfast lead to overeating later? (1:07:19) Does late-night eating disrupt sleep more than blue light? (1:08:59) Can one bad night's sleep trigger insulin resistance? (1:12:23) Can air pollution cause weight gain? (1:16:15) Vaping vs. smoking—which is worse for metabolic health? (1:17:40) Can statins and antidepressants trigger weight gain? (1:20:22) How to reverse insulin resistance in 90 days (1:26:59) Does apple cider vinegar really lower blood sugar? (1:30:54) Ketone supplements—are the metabolic benefits real? (1:36:34) Why some ethnicities get diabetes without obesity (1:44:28) How oversized fat cells trigger metabolic chaos (1:49:28) Do seed oils silently promote insulin resistance? (1:52:44) Seed oils—always harmful or only when heated? (1:58:35) Fat, muscle, or liver—where does insulin resistance start? (2:04:21) Do fat cells shrink or disappear with weight loss? (2:07:05) Are shrunken fat cells still insulin resistant? (2:08:15) Can exercise and cold therapy specifically shrink visceral fat? (2:09:40) Injecting insulin for muscle—are the risks worth it? (2:12:45) Are drugs like Ozempic a shortcut or solution for obesity? (2:19:12) Are current GLP-1 agonist doses too high? (2:20:02) Microdosing GLP-1 drugs—a solution for carb cravings? (2:26:01) Do these medications cause muscle loss—or is it poor nutrition? (2:28:30) Do GLP-1 agonist benefits extend beyond weight loss? (2:30:41) Could these treatments actually promote longevity? (2:36:12) The dark side of GLP-1 drugs—can they trigger depression? (2:39:31) Insulin vs. glucose—what really drives accelerated aging? (2:44:34) How high glucose levels damage cells—from glycolysis to sorbitol (2:46:40) How insulin shuts down your body's stress defenses (2:51:15) Which biomarkers best predict biological aging? (2:55:05) One simple breakfast change to lower insulin (2:57:19) Does eating dinner early improve insulin sensitivity? Show notes, transcript, and summary are available by clicking here Watch this episode on YouTube